Mathew P. Leese : rechercher sur Z-Library

David W. Knight, Mathew P. Leese

Année:

2000

Fichier:

PDF, 32 KB

2000

ChemInform Abstract: A Survey of Suitable Protecting Groups for the Synthesis of Hydroxylamines by Mitsunobu Reactions.

Journal:

David W. Knight, Mathew P. Leese, Norbert De Kimpe

Année:

2001

Fichier:

PDF, 29 KB

2001

ChemInform Abstract: The Synthesis of N-Hydroxyisoindolines by Reverse-Cope Chemistry.

Journal:

Mathew P. Leese, Simon P. Newman, Atul Purohit, Michael J. Reed, Barry V. L. Potter

Année:

2001

Fichier:

PDF, 28 KB

2001

2-Alkylsulfanyl Estrogen Derivatives: Synthesis of a Novel Class of Multi-Targeted Antitumor Agents.

Journal:

Simon P. Newman, Mathew P. Leese, Atul Purohit, David R.C. James, Catherine E. Rennie, Barry V.L. Potter, Michael J. Reed

Année:

2004

Fichier:

PDF, 33 KB

2004

Inhibition of in vitro angiogenesis by 2-methoxy- and 2-ethyl-estrogen sulfamates

Journal:

International Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 232 KB

english, 2004

Inhibition of MDA-MB-231 cell cycle progression and cell proliferation by C-2-substituted oestradiol mono- and bis-3-O-sulphamates

Bindumalini Raobaikady, Michael J. Reed, Mathew P. Leese, Barry V.L. Potter, Atul Purohit

Journal:

International Journal of Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 485 KB

english, 2005

2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents

Mathew P. Leese, Simon P. Newman, Atul Purohit, Michael J. Reed, Barry V.L. Potter

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 250 KB

english, 2004

The synthesis of N-hydroxyisoindolines by reverse-Cope chemistry

David W Knight, Mathew P Leese, Norbert De Kimpe

Journal:

David W Knight, Mathew P Leese

Année:

2001

Langue:

english

Fichier:

PDF, 71 KB

english, 2001

A survey of suitable protecting groups for the synthesis of hydroxylamines by Mitsunobu reactions

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 60 KB

english, 2001

Allene formation by the reaction of olefins with propargyl silyl ethers mediated by a zirconocene complex

Tamotsu Takahashi, Ryuichiro Hara, Shouquan Huo, Yasuyuki Ura, Mathew P. Leese, Noriyuki Suzuki

Journal:

Breast Cancer Research and Treatment

Année:

1997

Langue:

english

Fichier:

PDF, 197 KB

english, 1997

Collaborative community based care for people and their families living with schizophrenia in India: protocol for a randomised controlled trial

Sudipto Chatterjee, Morven Leese, Mirja Koschorke, Paul McCrone, Smita Naik, Sujit John, Hamid Dabholkar, Kimberley Goldsmith, Madhumitha Balaji, Mathew Varghese, Rangaswamy Thara, Vikram Patel, Graha

Journal:

Trials

Année:

2011

Langue:

english

Fichier:

PDF, 347 KB

english, 2011

2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex

Paul A. Foster, Yaik T. Ho, Simon P. Newman, Philip G. Kasprzyk, Mathew P. Leese, Barry V. L. Potter, Michael J. Reed, Atul Purohit

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 483 KB

english, 2008

A new, stereoselective approach to pyrrolidine-N-oxides by sequential condensation of sulfones with nitrones and reverse-cope elimination

Andrew R. Wheildon, David W. Knight, Mathew P. Leese

Journal:

Leese, Mathew P., Jourdan, Fabrice, Kimberley, Meriel R., Cozier, Gyles E., Thiyagarajan, Nethaji, Stengel, Chloe, Regis-Lydi, Sandra, Foster, Paul A., Newman, Simon P., Acharya, K. Ravi

Année:

1997

Langue:

english

Fichier:

PDF, 193 KB

english, 1997

Chimeric microtubule disruptors

Journal:

Chemical Communications

Année:

2010

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2010

2-Difluoromethyloestrone 3-O-sulphamate, a highly potent steroid sulphatase inhibitor

Julie E Reed, L.W Lawrence Woo, James J Robinson, Bertrand Leblond, Mathew P Leese, Atul Purohit, Michael J Reed, Barry V.L Potter

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 256 KB

english, 2004

Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate

Bindumalini Raobaikady, Atul Purohit, Surinder K. Chander, L.W.Lawrence Woo, Mathew P. Leese, Barry V.L. Potter, Michael J. Reed

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2003

Langue:

english

Fichier:

PDF, 195 KB

english, 2003

Structure–Activity Relationships of C-17-Substituted Estratriene-3- O -sulfamates as Anticancer Agents

Jourdan, Fabrice, Leese, Mathew P., Dohle, Wolfgang, Ferrandis, Eric, Newman, Simon P., Chander, Surinder, Purohit, Atul, Potter, Barry V. L.

Journal:

Leese, Mathew P., Leblond, Bertrand, Smith, Andrew, Newman, Simon P., Di Fiore, Anna, De Simone, Giuseppina, Supuran, Claudiu T., Purohit, Atul, Reed, Michael J., Potter, Barry V. L.

Année:

2011

Langue:

english

Fichier:

PDF, 2.62 MB

english, 2011

2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity †

Journal:

Organic & Biomolecular Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 411 KB

english, 2006

Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling

Jourdan, Fabrice, Bubert, Christian, Leese, Mathew P., Smith, Andrew, Ferrandis, Eric, Regis-Lydi, Sandra, Newman, Simon P., Purohit, Atul, Reed, Michael J., Potter, Barry V. L.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 385 KB

english, 2008

3,17-Disubstituted 2-Alkylestra-1,3,5(10)-trien-3-ol Derivatives: Synthesis, In Vitro and In Vivo Anticancer Activity

Bubert, Christian, Leese, Mathew P., Mahon, Mary F., Ferrandis, Eric, Regis-Lydi, Sandra, Kasprzyk, Philip G., Newman, Simon P., Ho, Yaik T., Purohit, Atul, Reed, Michael J., Potter, Barry V. L.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 366 KB

english, 2007

Synthesis, Antitubulin, and Antiproliferative SAR of Analogues of 2-Methoxyestradiol-3,17- O , O -bis-sulfamate

Jourdan, Fabrice, Leese, Mathew P., Dohle, Wolfgang, Hamel, Ernest, Ferrandis, Eric, Newman, Simon P., Purohit, Atul, Reed, Michael J., Potter, Barry V. L.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2010

Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors

Leese, Mathew P., Jourdan, Fabrice L., Major, Meriel R., Dohle, Wolfgang, Hamel, Ernest, Ferrandis, Eric, Fiore, Ann, Kasprzyk, Philip G., Potter, Barry V. L.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 927 KB

english, 2014

Synthesis, Anti-tubulin and Antiproliferative SAR of Steroidomimetic Dihydroisoquinolinones

Leese, Mathew P., Jourdan, Fabrice L., Major, Meriel R., Dohle, Wolfgang, Thomas, Mark P., Hamel, Ernest, Ferrandis, Eric, Mahon, Mary F., Newman, Simon P., Purohit, Atul, Potter, Barry V. L.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 761 KB

english, 2014

Synthesis, Antitubulin, and Antiproliferative SAR of C3/C1-Substituted Tetrahydroisoquinolines

Dohle, Wolfgang, Leese, Mathew P., Jourdan, Fabrice L., Major, Meriel R., Bai, Ruoli, Hamel, Ernest, Ferrandis, Eric, Kasprzyk, Philip G., Fiore, Ann, Newman, Simon P., Purohit, Atul, Potter, Barry V.

Journal:

Cozier, Gyles E., Leese, Mathew P., Lloyd, Matthew D., Baker, Matthew D., Thiyagarajan, Nethaji, Acharya, K. Ravi, Potter, Barry V. L.

Année:

2014

Langue:

english

Fichier:

PDF, 671 KB

english, 2014

Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Nonsteroidal Inhibitors ,

Journal:

Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 5.81 MB

english, 2010

StructureâActivity Relationships of C-17 Cyano-Substituted Estratrienes as Anticancer Agents â

Leese, Mathew P., Jourdan, Fabrice L., Gaukroger, Keira, Mahon, Mary F., Newman, Simon P., Foster, Paul A., Stengel, Chloe, Regis-Lydi, Sandra, Ferrandis, Eric, Fiore, Anna Di, De Simone, Giuseppina,

Journal:

Anson, Michael S., Leese, Mathew P., Tonks, Louise, Williams, Jonathan M. J.

Année:

2008

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2008

Transition metal catalysed reactions using glass bead technology

Journal:

Journal of the Chemical Society Dalton Transactions

Année:

1998

Langue:

english

Fichier:

PDF, 524 KB

english, 1998

A-Ring-Substituted Estrogen-3- O -sulfamates: Potent Multitargeted Anticancer Agents

Leese, Mathew P., Hejaz, Hatem A. M., Mahon, Mary F., Newman, Simon P., Purohit, Atul, Reed, Michael J., Potter, Barry V. L.

Journal:

ACS Medicinal Chemistry Letters

Année:

2005

Langue:

english

Fichier:

PDF, 219 KB

english, 2005

Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors

Leese, Mathew P., Jourdan, Fabrice, Dohle, Wolfgang, Kimberley, Meriel R., Thomas, Mark P., Bai, Ruoli, Hamel, Ernest, Ferrandis, Eric, Potter, Barry V. L.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 978 KB

english, 2012

Cover Picture: Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors (ChemMedChem 1/2014)

Leese, Mathew P., Jourdan, Fabrice L., Major, Meriel R., Dohle, Wolfgang, Hamel, Ernest, Ferrandis, Eric, Fiore, Ann, Kasprzyk, Philip G., Potter, Barry V. L.

Journal:

Dohle, Wolfgang, Leese, Mathew P., Jourdan, Fabrice L., Chapman, Christopher J., Hamel, Ernest, Ferrandis, Eric, Potter, Barry V. L.

Année:

2014

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2014

Optimisation of Tetrahydroisoquinoline-Based Chimeric Microtubule Disruptors

Journal: